Healthy Brains Network

Healthy brains

Overview

The Child Mind Institute has launched the Healthy Brain Network, an ongoing initiative focused on creating and sharing a biobank comprised of data from 10,000 New York City area children and adolescents (ages 5-21).

• Population: ages 5-21, children who likely have one or more psychiatric symptoms
• Data collected:
  • MRI + fMRI: movies (~10 min), predictive eye estimation regression - 3444 participants
  • Phenotypic assessment - 4080 participants
  • Physical activity
  • Behavioral measures (questionnaires)
  • Family structures (stress, trauma)
  • Substance use/addiction
  • Cognition and language tasks
  • Disorder-specific questionnaires
  • Electroencephalography
  • Digital Voice and Video Recordings
  • Genetics
  • Actigraphy
  • Cognitive Tasks (e.g., sequence learning), naturalistic stimuli
  • Eyetracking: pupil dilation and eye position

Phenotypic Assessment Protocol

Data Storage

• Which data are on openmind?
  • Imaging (rest, naturalistic)
  • Demographic info
  • Cognitive/Behavioral results
  • Clinical disorders
• What is the format?
  • raw, derivatives
• Which releases are available?
  • currently there are 10 releases of HBN imaging and phenotypic data
• Have imaging data been preprocessed?
  • fmriprep (no)
  • freesurfer (no)
  • first-level glms (no)
• MRI data have been preprocessed using Mindboggle and are available in S3 under the directory
• There is also a subset of HBN data that contain task information available here
• Where are the data stored on openmind?
  • are these data being transitioned to datalad?
• How does a new user get access to the dataset?
  • anyone with gablab group permissions should be able to access the data

MRI and fMRI Data Preprocessing

• Use xcp-D package to do post-processing of resting state data (basically picks up where fMRIPrep left off)
• This package also works on outputs from minimially preprocessed HCP data

Data on Openmind

• Phenotypic and behavioral data are stored here: /nese/mit/group/sig/projects/hbn/
• HBN BIDS data are here: /nese/mit/group/sig/projects/hbn/hbn_bids
• HBN derivatives are here: /nese/mit/group/sig/projects/hbn/hbn_bids/derivatives
  • derivatives include: fmriprep_23.0.0, xcp_d_0.4.0rc2